Centre Algatech

Institute of Michrobiology, Academy of Sciences of the Czech Republic

C4Sys - Center for Systems Biology http://c4sys.cz/
Registration number	For years	Project name	Total subsidy (in thousands CZK)	Description of the project
C4SYS	2016-2019	C4Sys - Center for Systems Biology prof. RNDr. Josef Komenda, DSc. Laboratory of Photosynthesis	5 864 000	The key topics covered are the biogenesis of photosynthetic apparatus, metabolism of photosynthetic pigments and structure and toxicity of cyanobacterial secondary metabolites. The team has long-term experience with photosynthetic organisms, and uses cutting-edge multidisciplinary techniques, optimized for studies with cyanobacteria. Focus: a spectrum of approaches to build and exploit predictive maps and models of complex biological systems that range from the molecular (genetic networks, snRNA, ion homeostathis, protein interaction networks etc) to the whole organism (yeast, bacteria, cynaobacteria, ticks) level, the design of experimental approaches (bioreactors, two-photon polarization microscopy, ion fluxes, metagenomics, isotope fingerprinting, stopped-flow, rapid-quench flow, ITC and DSC microcalorimetry, microfluidics, CD-spectroscopy, robotic GC spectrometry, ChIP techniques) to efficiently collect data that are fit for modelling and stewardship of relevant data, models and maps.

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Laboratory of Photosynthesis