| Name: | James Steven McCabe, MRes Laboratory of Photosynthesis Jan Janouškovec´s group |
|---|---|
| Phone: | +420 384 340 448 |
| E-mail: | mccabe(at)alga.cz |
| Position: | Research assistant |
James Steven McCabe
ORCID: 0009-0002-9142-4548
Research Interests
James´ interests primarily centre around understanding the evolution of parasitism in single-celled eukaryotes (protists). His current research is focused on the mechanisms governing evolution of endosymbiotic organelles, such as plastids and mitochondria, in apicomplexans, dinoflagellates and their free-living relatives. This mostly focuses on reductive evolution, i.e. genome reduction as well as protein translocation and cellular metabolism.
Figure: Isoprenoid dependency recapitulates apicomplexan, chromerid and squirmid plastid evolution. (A) Coulson plots indicating presence and absence of plastid-associated biosynthetic metabolites in the ACS clade associated with four core pathways: isoprenoid, iron-sulfur cluster, type II fatty acid, and heme biosynthesis. (B) Multiprotein phylogeny of the non-mevalonate pathway for biosynthesis of isoprenoid precursors in the ACS clade and plastid-bearing relatives.
Curriculum vitae
- 2024 – present: Research Assistant at Centre Algatech, Institute of Microbiology of the Czech Academy of Sciences, Třeboň, CZ
- 2022 – 2024: Master of Research (MRes) in Evolution at the School of Biological Sciences, University of Southampton
- 2015 – 2018: BSc (Hons) in Wildlife Conservation at the School of Biological and Environmental Sciences, Liverpool John Moores University