Curriculum vitae

Paulina Duhita Anindita, D.V.M., Ph.D.

Affiliation

Institute of Microbiology, Czech Academy of Sciences (CAS), Centre Algatech, Novohradská 237 - Opatovický mlýn, 379 81 Třeboň, CZ

ORCID: 0000-0001-9885-5813

Appointment

Associated Scientist

Education

• 2017, Ph.D. in Molecular virology, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan
• 2012, D.V.M., Faculty of Veterinary Medicine, Gadjah Mada University, Yogyakarta, Indonesia

Employment

• 2024 - present, Associate Scientist, Centre Algatech, Institute of Microbiology, CAS, CZ
• 2022 - 2024, Research fellow, LKC-Medicine, Nanyang Technological University, Singapore
• 2019 - 2022, Postdoctoral fellow, Faculty of Science, University of South Bohemia, CZ
• 2017 - 2018, Postdoctoral fellow, Hokkaido University Research Center for Zoonosis Control, Sapporo, Japan

Internship, courses, workshops, and certification

• 2024, Agile Project Management, Google Project Management Course, online
• 2019, EMBO Practical Course: Practical Integrative Structural Biology, EMBL Hamburg, Germany
• 2019, EMBO Workshop: Tools for Structural Biology of Membrane Proteins, EMBL Hamburg, Germany
• 2017, Certification of Zoonosis Control Expert, Hokkaido University, Sapporo, Japan
• 2016, Internship, Prof. Denis Shields’ Lab, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Ireland (1 month stay)

Research interest and current research work

- Regulation of cyanobacterial plasmid copy number

- Structural and functional study of viral proteins

- Antiviral development toward RNA viruses

- Discovery and molecular epidemiology of novel viruses

Student mentoring and supervision

• Co-supervisor of 1 Bc. and 1 MSc. students (both theses completed), Faculty of Science, University of South Bohemia, CZ
• Reviewer of 1 Bc. thesis, Faculty of Science, University of South Bohemia, CZ
• Mentor of 1 intern and 1 attachment students, Nanyang Technological University, SG

Selected conference talk

• 2019, Midwest AViDD Center – 3rd Workshop, Minnesota, USA, “ZIKV protease inhibitors update”
• 2021, The 25th IUCr Congress, Prague, Czech Republic, “Mechanism of RNA-stimulated ATP hydrolysis by tick-borne encephalitis virus (TBEV) NS3 helicase”
• 2021, The 26th Annual Congress of Czech and Slovak Societies for Biochemistry and Molecular Biology, Czech Republic, “Structural snapshots of ATPase cycle of tick-borne encephalitis virus helicase”
• 2018, The 3rd Hokkaido University Interdisciplinary Symposium, Sapporo, Japan, “Potent in vitro anti-rabies virus effect of a ribavirin analog”

Selected conference poster

• 2019, The 10th International Virus Assembly Symposium, Portugal, “Allosteric coupling between RNA binding and ATP hydrolysis in the tick-borne encephalitis virus helicase”
• 2017, The 65th Annual Meeting of the Japanese Society for Virology, Osaka, Japan, “Antiviral activity of ribavirin related compounds against rabies virus in vitro”
• 2014, The 37th Annual Meeting of the Molecular Biology Society of Japan, Yokohama, Japan, “Phylogenetic analysis of bat coronavirus from fruit bats in Indonesia”

Publication matrix

Total research articles: 12 (6 first-authored, 6 co-authored)
Total citations: 246 (Scopus), 341 (Google Scholar)
H-Index: 9 (Scopus), 10 (Google Scholar)

Selected publications

1. Anindita, PD, Otsuka, Y., Lattmann, S., Ngo, K.H., Liew, C.W., Kang CB, Harris, R.S., Scampavia, L., Spicer, T.P., and Luo D. 2024. A high-throughput cell-based screening method for Zika virus protease inhibitor discovery. SLAS Discovery. DOI: 10.1016/j.slasd.2024.100164.
2. Anindita, PD, Halbeisen, M., Reha, D., Tuma, R., and Franta, Z. 2022. Mechanistic insight into the RNA stimulated-ATPase activity of tick-borne encephalitis virus helicase. J Biol Chem. DOI: 10.1016/j.jbc.2022.102383.
3. Orba, Y, Hang'ombe, BM, Mweene, AS, Wada, Y, Anindita, PD, Phongphaew, W, Qiu, Y, Kajihara, M, Mori-Kajihara, A, Eto, Y, Sasaki, M, Hall, WW, Eshita, Y, Sawa, H. 2018. First isolation of West Nile virus in Zambia from mosquitoes. Transbound. Emerg. Dis. DOI: 10.1111/tbed.12888.
4. Anindita, PD, Sasaki, M, Okada, K, Ito, N, Sugiyama, M, Saito-Tarashima, N, Minakawa, N, Shuto, S, Otsuguro, S, Ichikawa, S, Matsuda, A, Maenaka, K, Orba, Y, and Sawa, H. 2018. Ribavirin-related compounds exert in vitro inhibitory effects toward rabies virus. Antiviral Res. DOI: 10.1016/j.antiviral.2018.03.011
5. Sasaki, M, Anindita, PD, Ito, N, Sugiyama, M, Carr, M, Fukuhara, H, Ose, T, Maenaka, K, Takada, A, Hall, WW, Orba, Y, Sawa, H. 2018. Heparan sulfate proteoglycans serve as an attachment factor for rabies virus entry and infection. J Infect Dis. DOI: 10.1093/infdis/jiy081.
6. Sasaki M, Orba Y, Anindita, PD, Ishii, A, Ueno, K, Hang’ombe, BM, Mweene, AS, Ito, K, Sawa, H. 2015. Distinct lineages of bufavirus in wild shrews and nonhuman primates. Emerg. Infect. Dis. DOI: 10.3201/eid2107.141969.